Table of Contents

• Preface by Prof. Stuart Pocock
• Foreword by the editors

Section I - General Principles and Reviews of Graphics

1. Concepts and Principles of Clinical Data Graphics
   Andreas Krause
2. Graphics for Exploratory Analysis and Data Discovery in the Life Sciences
   Michael O'Connell, Ian Cook, Difei Luo and Josh Patel
3. Grables: Visual Displays That Combine the Best Attributes of Graphs and Tables
   Thomas E. Bradstreet
4. The Use of Figures in Epidemiological Publications: A Survey of Current Practice and Consequent Recommendations
   Elisabeth Wreford Andersen and Stuart J. Pocock

Section II - Early Clinical Development

5. Use of Graphics for Studies with Small Sample Sizes: A Simulated Case Study of an Early-Phase Asset for Treatment of Type 2 Diabetes Mellitus (T2DM)
   Denise Shortino, Ann Walker, Andrew Miskell
6. Exploring Pharmacokinetic and Pharmacodynamic Data
   Charles Roosen, Richard Pugh and Andrew Nicholls
7. (Interactive) Graphics for Biomarker Assessment
   Michael Merz
8. Graphical Displays for Biomarker Data
   Manuela Zucknick, Thomas Hielscher, Martin Sill and Axel Benner

Section III - Clinical Trial Graphics

9. Statistical Graphics in Clinical Oncology
   Kye Gilder
10. Efficient and Effective Review of Clinical Trial Data Safety Using Interactive Graphs and Tables
    Harry Southworth
11. Visualizing Dose-Response when the Signal to Noise Ratio is Low: The Bronchodilatory Response in Chronic Obstructive Pulmonary Disease
    Michael Looby and Didier Renard
12. Statistical Graphics in Late-Stage Drug Development
    Julia Wang and Surya Mohanty
13. Graphical Data Exploration in QT Model Building and Cardiovascular Drug Safety
    Ihab G. Girgis and Surya Mohanty
14. Data Visualization at the Individual Patient Level
    Matthew Austin and Alicia Zhang
15. Graphics for Meta-Analysis
    Peter W. Lane, Judith Anzures-Cabrera, Steff Lewis and Jeffrey Tomlinson
16. Visualization of QT Data for Thorough QT Study Analysis and Review
    Christoffer W. Tornĝe
17. Graphics for Safety Analysis
    Peter W. Lane and Ohad Amit
18. Cardiac Safety
    Richard J. Anziano

Section IV - Operations Marketing and Post-Approval

19. Data Visualization for Clinical Trials Data Management and Operations
    Ted Snyder
20. Post-Approval Uses of Clinical Data, Phase IV Data, and Sales & Marketing Data Visualizations
    Sam Weerahandi, Birol Emir and Ed Whalen
21. Using Exploratory Visualization in the Analysis of Medical Product Safety in Observational Healthcare Data
    Patrick Ryan